- Ementa:
- O câncer apresenta-se como importante problema na saúde única, exibindo elevada morbidade e mortalidade em todo o mundo. Sua incidência tem crescido nos animais de companhia, em particular em cães e gatos, associado à maior sobrevida em animais domiciliados. Em paralelo, o conhecimento da biologia do processo cresce exponencialmente nas últimas décadas, em particular atrelado ao avanço da biologia molecular. Neste contexto, a disciplina visa abordar elementos relevantes da biologia tumoral, salientando aspectos de oncologia comparada, dentro de um enfoque celular e molecular, destacando-se: Epidemiologia das neoplasias; Oncologia comparada; Conceito, classificação e diferenças entre neoplasias benignas e malignas, protocolos de graduação neoplásica; Princípios de diagnóstico oncológico: cito e histopatologia; Genética e epigenética no câncer; "Hallmarks of cancer"; Microambiente tumoral: imunidade, fibroplasia e vasculogênese tumoral (significado biológico, contexto molecular, padrões de organização, marcadores e quantificação); Mecanismos de disseminação de tumores.
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